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RNA sequencing identifies clonal structure of T-cell repertoires in patients with adult T-cell leukemia/lymphoma

The diversity of T-cell receptor (TCR) repertoires, as generated by somatic DNA rearrangements, is central to immune system function. High-throughput sequencing technologies now allow examination of antigen receptor repertoires at single-nucleotide and, more recently, single-cell resolution. The TCR...

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Dades bibliogràfiques
Publicat a:NPJ Genom Med
Autors principals: Farmanbar, Amir, Kneller, Robert, Firouzi, Sanaz
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6502857/
https://ncbi.nlm.nih.gov/pubmed/31069115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41525-019-0084-9
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