Clonality of HTLV-1–infected T cells as a risk indicator for development and progression of adult T-cell leukemia

Adult T-cell leukemia (ATL) is an aggressive T-cell malignancy caused by human T-cell leukemia virus type 1 (HTLV-1) that develops along a carcinogenic process involving 5 or more genetic events in infected cells. The lifetime incidence of ATL among HTLV-1–infected individuals is approximately 5%. A...

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Vydáno v:Blood Adv
Hlavní autoři: Firouzi, Sanaz, Farmanbar, Amir, Nakai, Kenta, Iwanaga, Masako, Uchimaru, Kaoru, Utsunomiya, Atae, Suzuki, Yutaka, Watanabe, Toshiki
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2017
Témata:
Lymphoid Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728319/
https://ncbi.nlm.nih.gov/pubmed/29296760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017005900
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