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Development and validation of a new high-throughput method to investigate the clonality of HTLV-1-infected cells based on provirus integration sites
Transformation and clonal proliferation of T-cells infected with human T-cell leukemia virus type-I (HTLV-1) cause adult T-cell leukemia. We took advantage of next-generation sequencing technology to develop and internally validate a new methodology for isolating integration sites and estimating the...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4097847/ https://ncbi.nlm.nih.gov/pubmed/25028597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm568 |
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