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Overexpression of aberrant Wnt5a and its effect on acquisition of malignant phenotypes in adult T-cell leukemia/lymphoma (ATL) cells

Wnt5a is a ligand of the non-canonical Wnt signaling pathway involved in cell differentiation, motility, and inflammatory response. Adult T-cell leukemia/lymphoma (ATL) is one of the most aggressive T-cell malignancies caused by infection of human T-cell leukemia virus type1 (HTLV-1). Among subtypes...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nakano, Kazumi, Chihara, Yohei, Kobayashi, Seiichiro, Iwanaga, Masako, Utsunomiya, Atae, Watanabe, Toshiki, Uchimaru, Kaoru
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7892546/
https://ncbi.nlm.nih.gov/pubmed/33603066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83613-2
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