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T cell receptor sequencing of early-stage breast cancer tumors identifies altered clonal structure of the T cell repertoire
Tumor-infiltrating T cells play an important role in many cancers, and can improve prognosis and yield therapeutic targets. We characterized T cells infiltrating both breast cancer tumors and the surrounding normal breast tissue to identify T cells specific to each, as well as their abundance in per...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5715779/ https://ncbi.nlm.nih.gov/pubmed/29138313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1713863114 |
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