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Nlrp3 inflammasome activation and Gasdermin D-driven pyroptosis are immunopathogenic upon gastrointestinal norovirus infection

Norovirus infection is the leading cause of food-borne gastroenteritis worldwide, being responsible for over 200,000 deaths annually. Studies with murine norovirus (MNV) showed that protective STAT1 signaling controls viral replication and pathogenesis, but the immune mechanisms that noroviruses exp...

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Bibliografiska uppgifter
I publikationen:PLoS Pathog
Huvudupphovsmän: Dubois, Hanne, Sorgeloos, Frederic, Sarvestani, Soroush T., Martens, Liesbet, Saeys, Yvan, Mackenzie, Jason M., Lamkanfi, Mohamed, van Loo, Geert, Goodfellow, Ian, Wullaert, Andy
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6502405/
https://ncbi.nlm.nih.gov/pubmed/31017981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007709
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