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Overcoming Endosomal Entrapment in Drug Delivery

Intracellular delivery of biological agents such as peptides, proteins, and nucleic acids generally rely on the endocytic pathway as the major uptake mechanism, resulting in their entrapment inside the endosome and lysosome. The recent discovery of cell-penetrating molecules of exceptionally high en...

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Bibliografiske detaljer
Udgivet i:Bioconjug Chem
Main Authors: Pei, Dehua, Buyanova, Marina
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6501178/
https://ncbi.nlm.nih.gov/pubmed/30525488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.8b00778
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