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Flap-site fragment restores back wild-type behaviour in resistant form of HIV protease
HIV-1 protease (HIV-PR) performs a vital step in the virus life cycle which makes it an excellent target for drug therapy. However, due to the error-prone of HIV reverse transcriptase, mutations in HIV-PR often occur, inducing drug-resistance to inhibitors. Some HIV-PR mutations can make the flaps o...
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| Publicado no: | Mol Inform |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6501176/ https://ncbi.nlm.nih.gov/pubmed/30051611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/minf.201800053 |
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