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Flap-site fragment restores back wild-type behaviour in resistant form of HIV protease

HIV-1 protease (HIV-PR) performs a vital step in the virus life cycle which makes it an excellent target for drug therapy. However, due to the error-prone of HIV reverse transcriptase, mutations in HIV-PR often occur, inducing drug-resistance to inhibitors. Some HIV-PR mutations can make the flaps o...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Inform
Egile Nagusiak: Luchi, Adriano, Angelina, Emilio, Bogado, Lucrecia, Forli, Stefano, Olson, Arthur, Peruchena, Nélida
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6501176/
https://ncbi.nlm.nih.gov/pubmed/30051611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/minf.201800053
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