Cereblon Control of Zebrafish Brain Size by Regulation of Neural Stem Cell Proliferation

Thalidomide is a teratogen that causes multiple malformations in the developing baby through its interaction with cereblon (CRBN), a substrate receptor subunit of the CRL4 E3 ubiquitin ligase complex. CRBN was originally reported as a gene associated with autosomal recessive non-syndromic mild menta...

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Vydáno v:iScience
Hlavní autoři: Ando, Hideki, Sato, Tomomi, Ito, Takumi, Yamamoto, Junichi, Sakamoto, Satoshi, Nitta, Nobuhiro, Asatsuma-Okumura, Tomoko, Shimizu, Nobuyuki, Mizushima, Ryota, Aoki, Ichio, Imai, Takeshi, Yamaguchi, Yuki, Berk, Arnold J., Handa, Hiroshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6501120/
https://ncbi.nlm.nih.gov/pubmed/31055217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.04.007
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