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Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine

Thalidomide, a sedative drug that was once excluded from the market owing to its teratogenic properties, was later found to be effective in treating multiple myeloma. We had previously demonstrated that cereblon (CRBN) is the target of thalidomide embryopathy and acts as a substrate receptor for the...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Sato, Tomomi, Ito, Takumi, Handa, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990905/
https://ncbi.nlm.nih.gov/pubmed/33777938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.629326
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