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Macrocyclic lactone anthelmintic-induced leukocyte binding to Dirofilaria immitis microfilariae: Influence of the drug resistance status of the parasite

The macrocyclic lactone anthelmintics are the only class of drug currently used to prevent heartworm disease. Their extremely high potency in vivo is not mirrored by their activity against Dirofilaria immitis larvae in vitro, leading to suggestions that they may require host immune functions to kill...

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Detalhes bibliográficos
Publicado no:Int J Parasitol Drugs Drug Resist
Main Authors: Berrafato, Tessa, Coates, Ruby, Reaves, Barbara J., Kulke, Daniel, Wolstenholme, Adrian J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500911/
https://ncbi.nlm.nih.gov/pubmed/31054498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2019.04.004
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