Laboratory assays reveal diverse phenotypes among microfilariae of Dirofilaria immitis isolates with known macrocyclic lactone susceptibility status

Prevention of canine heartworm disease caused by Dirofilaria immitis relies on chemoprophylaxis with macrocyclic lactone anthelmintics. Alarmingly, there are increased reports of D. immitis isolates with resistance to macrocyclic lactones and the ability to break through prophylaxis. Yet, there is n...

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Udgivet i:PLoS One
Main Authors: Jesudoss Chelladurai, Jeba R. J., Martin, Katy A., Chinchilla-Vargas, Krystal, Jimenez Castro, Pablo D., Kaplan, Ray M., Brewer, Matthew T.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7410292/
https://ncbi.nlm.nih.gov/pubmed/32760111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0237150
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