Surgery for Glioblastoma in Light of Molecular Markers: Impact of Resection and MGMT Promoter Methylation in Newly Diagnosed IDH-1 Wild-Type Glioblastomas

BACKGROUND: Previous studies addressing the influence of surgery on the outcome of patients with glioblastomas (GBM) have not addressed molecular markers. The value of surgery versus the tumor's major biological markers remains unclear. OBJECTIVE: We investigate the extent of resection as a pro...

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Bibliografiska uppgifter
I publikationen:Neurosurgery
Huvudupphovsmän: Gessler, Florian, Bernstock, Joshua D, Braczynski, Anne, Lescher, Stephanie, Baumgarten, Peter, Harter, Patrick N, Mittelbronn, Michel, Wu, Tianxia, Seifert, Volker, Senft, Christian
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2019
Ämnen:
Research—Human—Clinical Studies
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500906/
https://ncbi.nlm.nih.gov/pubmed/29617848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuros/nyy049
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