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Surgery for Glioblastoma in Light of Molecular Markers: Impact of Resection and MGMT Promoter Methylation in Newly Diagnosed IDH-1 Wild-Type Glioblastomas

BACKGROUND: Previous studies addressing the influence of surgery on the outcome of patients with glioblastomas (GBM) have not addressed molecular markers. The value of surgery versus the tumor's major biological markers remains unclear. OBJECTIVE: We investigate the extent of resection as a pro...

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Detalhes bibliográficos
Publicado no:Neurosurgery
Main Authors: Gessler, Florian, Bernstock, Joshua D, Braczynski, Anne, Lescher, Stephanie, Baumgarten, Peter, Harter, Patrick N, Mittelbronn, Michel, Wu, Tianxia, Seifert, Volker, Senft, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500906/
https://ncbi.nlm.nih.gov/pubmed/29617848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuros/nyy049
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