Surgery for Glioblastoma in Light of Molecular Markers: Impact of Resection and MGMT Promoter Methylation in Newly Diagnosed IDH-1 Wild-Type Glioblastomas

BACKGROUND: Previous studies addressing the influence of surgery on the outcome of patients with glioblastomas (GBM) have not addressed molecular markers. The value of surgery versus the tumor's major biological markers remains unclear. OBJECTIVE: We investigate the extent of resection as a pro...

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Bibliographic Details
Published in:Neurosurgery
Main Authors: Gessler, Florian, Bernstock, Joshua D, Braczynski, Anne, Lescher, Stephanie, Baumgarten, Peter, Harter, Patrick N, Mittelbronn, Michel, Wu, Tianxia, Seifert, Volker, Senft, Christian
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Research—Human—Clinical Studies
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500906/
https://ncbi.nlm.nih.gov/pubmed/29617848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuros/nyy049
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