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Mesenchymal Stem Cells Reverse Diabetic Nephropathy Disease via Lipoxin A4 by Targeting Transforming Growth Factor β (TGF-β)/smad Pathway and Pro-Inflammatory Cytokines

BACKGROUND: Diabetic nephropathy (DN) is the leading cause of end-stage renal disease. Mesenchymal stem cells (MSCs) treatment has been proved to be effective in DN models by protecting renal function and preventing fibrosis. However, the underlying mechanism is unclear. Previous research indicated...

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Dettagli Bibliografici
Pubblicato in:Med Sci Monit
Autori principali: Bai, Yihua, Wang, Jiaping, He, Zhenkun, Yang, Min, Li, Luohua, Jiang, Hongying
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Scientific Literature, Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500104/
https://ncbi.nlm.nih.gov/pubmed/31023998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.914860
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