Mesenchymal Stem Cells Reverse Diabetic Nephropathy Disease via Lipoxin A4 by Targeting Transforming Growth Factor β (TGF-β)/smad Pathway and Pro-Inflammatory Cytokines

BACKGROUND: Diabetic nephropathy (DN) is the leading cause of end-stage renal disease. Mesenchymal stem cells (MSCs) treatment has been proved to be effective in DN models by protecting renal function and preventing fibrosis. However, the underlying mechanism is unclear. Previous research indicated...

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Publicat a:Med Sci Monit
Autors principals: Bai, Yihua, Wang, Jiaping, He, Zhenkun, Yang, Min, Li, Luohua, Jiang, Hongying
Format: Artigo
Idioma:Inglês
Publicat: International Scientific Literature, Inc. 2019
Matèries:
Animal Study
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500104/
https://ncbi.nlm.nih.gov/pubmed/31023998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.914860
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