Safety and clinical activity of PD-L1 blockade in patients with aggressive recurrent respiratory papillomatosis

BACKGROUND: Recurrent respiratory papillomatosis (RRP) is a human papillomavirus (HPV)-driven disorder that causes substantial morbidity and can lead to fatal distal airway obstruction and post-obstructive pneumonias. Patients require frequent surgical debridement of disease, and no approved systemi...

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Veröffentlicht in:J Immunother Cancer
Hauptverfasser: Allen, Clint T., Lee, Sunmin, Norberg, Scott M., Kovalovsky, Damian, Ye, Hong, Clavijo, Paul E., Hu-Lieskovan, Siwen, Schlegel, Richard, Schlom, Jeffrey, Strauss, Julius, Gulley, James L., Trepel, Jane, Hinrichs, Christian S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500000/
https://ncbi.nlm.nih.gov/pubmed/31053174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0603-3
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