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Mechanisms of Resistance to PD-1 and PD-L1 blockade

Cancer immunotherapy utilizing blockade of the PD-1/PD-L1 checkpoint has revolutionized the treatment of a wide variety of malignancies, leading to durable therapeutic responses not typically seen with traditional cytotoxic anti-cancer agents. However, these therapies are ineffective in a significan...

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Detalhes bibliográficos
Publicado no:Cancer J
Main Authors: Nowicki, Theodore S., Hu-Lieskovan, Siwen, Ribas, Antoni
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785093/
https://ncbi.nlm.nih.gov/pubmed/29360728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0000000000000303
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