LncRNA SNHG1 contributes to sorafenib resistance by activating the Akt pathway and is positively regulated by miR-21 in hepatocellular carcinoma cells

BACKGROUND: Acquired resistance to sorafenib greatly limits its therapeutic efficiency in the treatment of hepatocellular carcinoma (HCC). Increasing evidence indicates that long noncoding RNAs (lncRNAs) play important roles in the resistance to anti-cancer drugs. The present study aims to explore t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Exp Clin Cancer Res
Päätekijät: Li, Weidong, Dong, Xuesong, He, Changjun, Tan, Gang, Li, Ziyi, Zhai, Bo, Feng, Jing, Jiang, Xian, Liu, Chang, Jiang, Hongchi, Sun, Xueying
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2019
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499991/
https://ncbi.nlm.nih.gov/pubmed/31053148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1177-0
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