Dual inhibition of Akt and c‐Met as a second‐line therapy following acquired resistance to sorafenib in hepatocellular carcinoma cells

Sorafenib displays a limited efficacy for advanced hepatocellular carcinoma (HCC). Some patients with HCC initially respond to sorafenib, but eventually succumb to the disease, indicating that the acquired resistance to sorafenib reduces its beneficial effects. No alternative drugs are available aft...

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Bibliografiske detaljer
Udgivet i:Mol Oncol
Main Authors: Han, Peng, Li, Hali, Jiang, Xian, Zhai, Bo, Tan, Gang, Zhao, Dali, Qiao, Haiquan, Liu, Bing, Jiang, Hongchi, Sun, Xueying
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527443/
https://ncbi.nlm.nih.gov/pubmed/28164434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12039
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