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APOBEC-induced mutations and their cancer effect size in head and neck squamous cell carcinoma

Recent studies have revealed the mutational signatures underlying the somatic evolution of cancer, and the prevalences of associated somatic genetic variants. Here we estimate the intensity of positive selection that drives mutations to high frequency in tumors, yielding higher prevalences than expe...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Oncogene
मुख्य लेखकों: Cannataro, Vincent L., Gaffney, Stephen G., Sasaki, Tomoaki, Issaeva, Natalia, Grewal, Nicholas K. S., Grandis, Jennifer R., Yarbrough, Wendell G., Burtness, Barbara, Anderson, Karen S., Townsend, Jeffrey P.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499643/
https://ncbi.nlm.nih.gov/pubmed/30647454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0657-6
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