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MDM2 integrates cellular respiration and apoptotic signaling through NDUFS1 and the mitochondrial network.
Signaling diversity and subsequent complexity in higher eukaryotes is partially explained by one gene encoding a polypeptide with multiple biochemical functions in different cellular contexts. For example, mouse double minute 2 (MDM2) is functionally characterized as both an oncogene and tumor suppr...
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| Publicado no: | Mol Cell |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6499641/ https://ncbi.nlm.nih.gov/pubmed/30879903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.02.012 |
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