Efficient delivery of small interfering RNAs targeting particular mRNAs into pancreatic cancer cells inhibits invasiveness and metastasis of pancreatic tumors

We report the use of small interfering RNAs (siRNAs) against ARHGEF4, CCDC88A, LAMTOR2, mTOR, NUP85, and WASF2 and folic acid (FA)-modified polyethylene glycol (PEG)-chitosan oligosaccharide lactate (COL) nanoparticles for targeting, imaging, delivery, gene silencing, and inhibition of invasiveness...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Taniuchi, Keisuke, Yawata, Toshio, Tsuboi, Makiko, Ueba, Tetsuya, Saibara, Toshiji
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499602/
https://ncbi.nlm.nih.gov/pubmed/31080558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26880
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