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BART Inhibits Pancreatic Cancer Cell Invasion by PKCα Inactivation through Binding to ANX7

A novel function for the binder of Arl two (BART) molecule in pancreatic cancer cells is reported. BART inhibits invasiveness of pancreatic cancer cells through binding to a Ca(2+)-dependent, phosphorylated, guanosine triphosphatase (GTPase) membrane fusion protein, annexin7 (ANX7). A tumor suppress...

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Autors principals: Taniuchi, Keisuke, Yokotani, Kunihiko, Saibara, Toshiji
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330813/
https://ncbi.nlm.nih.gov/pubmed/22532868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035674
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