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IGF2BP3-mediated translation in cell protrusions promotes cell invasiveness and metastasis of pancreatic cancer

Pancreatic cancers are aggressive because they are highly invasive and highly metastatic; moreover, effective treatments for aggressive pancreatic cancers are lacking. Here, we report that IGF2BP3 promoted the invasiveness and metastasis of pancreatic cancers through locally translated IGF2BP3-bound...

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Detalhes bibliográficos
Main Authors: Taniuchi, Keisuke, Furihata, Mutsuo, Hanazaki, Kazuhiro, Saito, Motoaki, Saibara, Toshiji
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196166/
https://ncbi.nlm.nih.gov/pubmed/25216519
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