The Influenza A Virus Endoribonuclease PA-X Usurps Host mRNA Processing Machinery to Limit Host Gene Expression

Many viruses shut off host gene expression to inhibit antiviral responses. Viral proteins and host proteins required for viral replication are typically spared in this process, but the mechanisms of target selectivity during host shutoff remain poorly understood. Using transcriptome-wide and targete...

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Publicado no:Cell Rep
Main Authors: Gaucherand, Lea, Porter, Brittany K., Levene, Rachel E., Price, Emma L., Schmaling, Summer K., Rycroft, Chris H., Kevorkian, Yuzo, McCormick, Craig, Khaperskyy, Denys A., Gaglia, Marta M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Authors. 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499400/
https://ncbi.nlm.nih.gov/pubmed/30995476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.03.063
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