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Selective Degradation of Host RNA Polymerase II Transcripts by Influenza A Virus PA-X Host Shutoff Protein

Influenza A viruses (IAVs) inhibit host gene expression by a process known as host shutoff. Host shutoff limits host innate immune responses and may also redirect the translation apparatus to the production of viral proteins. Multiple IAV proteins regulate host shutoff, including PA-X, a ribonucleas...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Khaperskyy, Denys A., Schmaling, Summer, Larkins-Ford, Jonah, McCormick, Craig, Gaglia, Marta M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744033/
https://ncbi.nlm.nih.gov/pubmed/26849127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005427
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