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Influenza A Virus Host Shutoff Disables Antiviral Stress-Induced Translation Arrest

Influenza A virus (IAV) polymerase complexes function in the nucleus of infected cells, generating mRNAs that bear 5′ caps and poly(A) tails, and which are exported to the cytoplasm and translated by host machinery. Host antiviral defences include mechanisms that detect the stress of virus infection...

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Detalhes bibliográficos
Main Authors: Khaperskyy, Denys A., Emara, Mohamed M., Johnston, Benjamin P., Anderson, Paul, Hatchette, Todd F., McCormick, Craig
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4092144/
https://ncbi.nlm.nih.gov/pubmed/25010204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004217
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