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The Influenza A Virus Host Shutoff Factor PA-X Is Rapidly Turned Over in a Strain-Specific Manner

The influenza A endoribonuclease PA-X regulates virulence and transmission of the virus by reducing host gene expression and thus regulating immune responses to influenza A virus. Despite this key function in viral biology, the levels of the PA-X protein remain markedly low during infection. Previou...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Levene, Rachel Emily, Shrestha, Shailab D., Gaglia, Marta Maria
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103685/
https://ncbi.nlm.nih.gov/pubmed/33504608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02312-20
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