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Access to P-chiral phosphine oxides by enantioselective allylic alkylation of bisphenols

A novel biscinchona alkaloid-catalyzed highly enantioselective desymmetrization reaction of bisphenol compounds with achiral Morita–Baylis–Hillman carbonate agents was developed. Through the asymmetric allylic alkylation strategy, a broad range of optically active P-stereogenic phosphine oxides were...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Yang, Guo-Hui, Li, Yao, Li, Xin, Cheng, Jin-Pei
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499109/
https://ncbi.nlm.nih.gov/pubmed/31105926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc05439h
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