Protein Kinase C δ Regulates the Depletion of Actin at the Immunological Synapse Required for Polarized Exosome Secretion by T Cells

Multivesicular bodies (MVB) are endocytic compartments that enclose intraluminal vesicles (ILVs) formed by inward budding from the limiting membrane of endosomes. In T lymphocytes, ILVs are secreted as Fas ligand-bearing, pro-apoptotic exosomes following T cell receptor (TCR)-induced fusion of MVB w...

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Vydáno v:Front Immunol
Hlavní autoři: Herranz, Gonzalo, Aguilera, Pablo, Dávila, Sergio, Sánchez, Alicia, Stancu, Bianca, Gómez, Jesús, Fernández-Moreno, David, de Martín, Raúl, Quintanilla, Mario, Fernández, Teresa, Rodríguez-Silvestre, Pablo, Márquez-Expósito, Laura, Bello-Gamboa, Ana, Fraile-Ramos, Alberto, Calvo, Víctor, Izquierdo, Manuel
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499072/
https://ncbi.nlm.nih.gov/pubmed/31105694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00851
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