Actin reorganization at the centrosomal area and the immune synapse regulates polarized secretory traffic of multivesicular bodies in T lymphocytes

T-cell receptor stimulation induces the convergence of multivesicular bodies towards the microtubule-organizing centre (MTOC) and the polarization of the MTOC to the immune synapse (IS). These events lead to exosome secretion at the IS. We describe here that upon IS formation centrosomal area F-acti...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Extracell Vesicles
Main Authors: Bello-Gamboa, Ana, Velasco, Marta, Moreno, Solange, Herranz, Gonzalo, Ilie, Roxana, Huetos, Silvia, Dávila, Sergio, Sánchez, Alicia, Bernardino De La Serna, Jorge, Calvo, Víctor, Izquierdo, Manuel
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7480611/
https://ncbi.nlm.nih.gov/pubmed/32939232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/20013078.2020.1759926
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