A targeted dominant negative mutation of the thyroid hormone α1 receptor causes increased mortality, infertility, and dwarfism in mice
Mutations in the thyroid hormone receptor β (TRβ) gene result in resistance to thyroid hormone. However, it is unknown whether mutations in the TRα gene could lead to a similar disease. To address this question, we prepared mutant mice by targeting mutant thyroid hormone receptor kindred PV (PV) mut...
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| I publikationen: | Proc Natl Acad Sci U S A |
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| Huvudupphov: | , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
National Academy of Sciences
2001
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| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC64989/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11734632/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.261565798 |
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