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Current Development of siRNA Bioconjugates: From Research to the Clinic
Small interfering RNAs (siRNAs) acting via RNA interference mechanisms are able to recognize a homologous mRNA sequence in the cell and induce its degradation. The main problems in the development of siRNA-based drugs for therapeutic use are the low efficiency of siRNA delivery to target cells and t...
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| Publié dans: | Front Pharmacol |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6498891/ https://ncbi.nlm.nih.gov/pubmed/31105570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00444 |
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