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Transcriptional repression by androgen receptor: roles in castration-resistant prostate cancer

Androgen receptor (AR), a hormonal transcription factor, plays important roles during prostate cancer progression and is a key target for therapeutic interventions. While androgen-deprivation therapies are initially successful in regressing prostate tumors, the disease ultimately comes back as castr...

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Опубликовано в: :Asian J Androl
Главные авторы: Gritsina, Galina, Gao, Wei-Qiang, Yu, Jindan
Формат: Artigo
Язык:Inglês
Опубликовано: Wolters Kluwer - Medknow 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498738/
https://ncbi.nlm.nih.gov/pubmed/30950412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/aja.aja_19_19
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