Sox2 Is an Androgen Receptor-Repressed Gene That Promotes Castration-Resistant Prostate Cancer

Despite advances in detection and therapy, castration-resistant prostate cancer continues to be a major clinical problem. The aberrant activity of stem cell pathways, and their regulation by the Androgen Receptor (AR), has the potential to provide insight into novel mechanisms and pathways to preven...

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Autori principali: Kregel, Steven, Kiriluk, Kyle J., Rosen, Alex M., Cai, Yi, Reyes, Edwin E., Otto, Kristen B., Tom, Westin, Paner, Gladell P., Szmulewitz, Russell Z., Vander Griend, Donald J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543364/
https://ncbi.nlm.nih.gov/pubmed/23326489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053701
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