Sox2 Is an Androgen Receptor-Repressed Gene That Promotes Castration-Resistant Prostate Cancer

Despite advances in detection and therapy, castration-resistant prostate cancer continues to be a major clinical problem. The aberrant activity of stem cell pathways, and their regulation by the Androgen Receptor (AR), has the potential to provide insight into novel mechanisms and pathways to preven...

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Autors principals: Kregel, Steven, Kiriluk, Kyle J., Rosen, Alex M., Cai, Yi, Reyes, Edwin E., Otto, Kristen B., Tom, Westin, Paner, Gladell P., Szmulewitz, Russell Z., Vander Griend, Donald J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543364/
https://ncbi.nlm.nih.gov/pubmed/23326489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053701
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