Glucocorticoid Receptor Activity Contributes to Resistance to Androgen-Targeted Therapy in Prostate Cancer

Despite new treatments for castrate-resistant prostate cancer (CRPC), the prognosis of patients with CRPC remains bleak due to acquired resistance to androgen receptor (AR)-directed therapy. The glucocorticoid receptor (GR) and AR share several transcriptional targets, including the anti-apoptotic g...

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Detalhes bibliográficos
Publicado no:Horm Cancer
Main Authors: Isikbay, Masis, Otto, Kristen, Kregel, Steven, Kach, Jacob, Cai, Yi, Vander Griend, Donald J., Conzen, Suzanne D., Szmulewitz, Russell Z.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440041/
https://ncbi.nlm.nih.gov/pubmed/24615402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12672-014-0173-2
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