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Recombination and mutation during long-term gastric colonization by Helicobacter pylori: Estimates of clock rates, recombination size, and minimal age

The bacterium Helicobacter pylori colonizes the gastric mucosa of half of the human population, resulting in chronic gastritis, ulcers, and cancer. We sequenced ten gene fragments from pairs of strains isolated sequentially at a mean interval of 1.8 years from 26 individuals. Several isolates had ac...

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Bibliografische gegevens
Hoofdauteurs: Falush, Daniel, Kraft, Christian, Taylor, Nancy S., Correa, Pelayo, Fox, James G., Achtman, Mark, Suerbaum, Sebastian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences 2001
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC64982/
https://ncbi.nlm.nih.gov/pubmed/11742075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.251396098
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