Vaccinia Virus BBK E3 Ligase Adaptor A55 Targets Importin-Dependent NF-κB Activation and Inhibits CD8(+) T-Cell Memory

Viral infection of cells is sensed by pathogen recognition receptors that trigger an antiviral innate immune response, and consequently viruses have evolved countermeasures. Vaccinia virus (VACV) evades the host immune response by expressing scores of immunomodulatory proteins. One family of VACV pr...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Pallett, Mitchell A., Ren, Hongwei, Zhang, Rui-Yao, Scutts, Simon R., Gonzalez, Laura, Zhu, Zihan, Maluquer de Motes, Carlos, Smith, Geoffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498060/
https://ncbi.nlm.nih.gov/pubmed/30814284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00051-19
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