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Vaccinia Virus Inhibits NF-κB-Dependent Gene Expression Downstream of p65 Translocation

The transcription factor nuclear factor kappa light-chain enhancer of activated B cells (NF-κB) plays a critical role in host defense against viral infection by inducing the production of proinflammatory mediators and type I interferon. Consequently, viruses have evolved many mechanisms to block its...

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Bibliografske podrobnosti
Main Authors: Sumner, Rebecca P., Maluquer de Motes, Carlos, Veyer, David L., Smith, Geoffrey L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957909/
https://ncbi.nlm.nih.gov/pubmed/24371075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02627-13
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