Analysis of the anti-apoptotic activity of four vaccinia virus proteins demonstrates that B13 is the most potent inhibitor in isolation and during viral infection

Vaccinia virus (VACV) is a large dsDNA virus encoding ~200 proteins, several of which inhibit apoptosis. Here, a comparative study of anti-apoptotic proteins N1, F1, B13 and Golgi anti-apoptotic protein (GAAP) in isolation and during viral infection is presented. VACVs strains engineered to lack eac...

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Publicat a:J Gen Virol
Autors principals: Veyer, David L., Maluquer de Motes, Carlos, Sumner, Rebecca P., Ludwig, Louisa, Johnson, Benjamin F., Smith, Geoffrey L.
Format: Artigo
Idioma:Inglês
Publicat: Society for General Microbiology 2014
Matèries:
Animal
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233632/
https://ncbi.nlm.nih.gov/pubmed/25090990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.068833-0
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