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Vaccinia virus protein A49 activates Wnt signalling by targetting the E3 ligase β-TrCP
Vaccinia virus (VACV) encodes multiple proteins inhibiting the NF-κB signalling pathway. One of these, A49, targets the E3 ubiquitin ligase β-TrCP, which is responsible for the ubiquitylation and consequential proteosomal degradation of IκBα and the release of the NF-κB heterodimer. β-TrCP is a plei...
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| Udgivet i: | J Gen Virol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Microbiology Society
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5845699/ https://ncbi.nlm.nih.gov/pubmed/29058646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000946 |
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