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Identification and functional analyses of disease-associated P4-ATPase phospholipid flippase variants in red blood cells
ATP-dependent phospholipid flippase activity crucial for generating lipid asymmetry was first detected in red blood cell (RBC) membranes, but the P4-ATPases responsible have not been directly determined. Using affinity-based MS, we show that ATP11C is the only abundant P4-ATPase phospholipid flippas...
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| Publicat a: | J Biol Chem |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6497962/ https://ncbi.nlm.nih.gov/pubmed/30850395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007270 |
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