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Identification of residues defining phospholipid flippase substrate specificity of type IV P-type ATPases

Type IV P-type ATPases (P4-ATPases) catalyze translocation of phospholipid across a membrane to establish an asymmetric bilayer structure with phosphatidylserine (PS) and phosphatidylethanolamine (PE) restricted to the cytosolic leaflet. The mechanism for how P4-ATPases recognize and flip phospholip...

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Detalles Bibliográficos
Main Authors: Baldridge, Ryan D., Graham, Todd R.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277569/
https://ncbi.nlm.nih.gov/pubmed/22308393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115725109
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