Constitutive SRC-mediated phosphorylation of pannexin 1 at tyrosine 198 occurs at the plasma membrane

Pannexin 1 (PANX1)-mediated ATP release in vascular smooth muscle coordinates α1-adrenergic receptor (α1-AR) vasoconstriction and blood pressure homeostasis. We recently identified amino acids 198–200 (YLK) on the PANX1 intracellular loop that are critical for α1-AR–mediated vasoconstriction and PAN...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: DeLalio, Leon J., Billaud, Marie, Ruddiman, Claire A., Johnstone, Scott R., Butcher, Joshua T., Wolpe, Abigail G., Jin, Xueyao, Keller, T. C. Stevenson, Keller, Alexander S., Rivière, Thibaud, Good, Miranda E., Best, Angela K., Lohman, Alexander W., Swayne, Leigh Anne, Penuela, Silvia, Thompson, Roger J., Lampe, Paul D., Yeager, Mark, Isakson, Brant E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2019
Gaiak:
Cell Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497939/
https://ncbi.nlm.nih.gov/pubmed/30814251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006982
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