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The Detrimental Effects of Kynurenine, a Tryptophan Metabolite, on Human Bone Metabolism

CONTEXT: Studies in aged mice support a role for kynurenine, a tryptophan metabolite, in age-induced bone loss; however, the role of kynurenine in human bone metabolism is not well understood. OBJECTIVE: To assess whether the kynurenine level in bone marrow (BM) aspirates, directly reflecting the bo...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Kim, Beom-Jun, Hamrick, Mark W, Yoo, Hyun Ju, Lee, Seung Hun, Kim, Su Jung, Koh, Jung-Min, Isales, Carlos M
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497841/
https://ncbi.nlm.nih.gov/pubmed/30715395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2018-02481
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