Statins may have double-edged effects in patients with lung adenocarcinoma after lung resection

Purpose: The epithelial to mesenchymal transition (EMT) is pivotal for driving metastasis and recurrence in lung cancer. Some in vitro reports have shown that statins suppress EMT by inactivating mutant p53 functions. Several clinical trials of conventional treatments with statins have been performe...

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Vydáno v:Cancer Manag Res
Hlavní autoři: Nishikawa, Shigeto, Menju, Toshi, Takahashi, Koji, Miyata, Ryo, Chen-Yoshikawa, Toyofumi Fengshi, Sonobe, Makoto, Yoshizawa, Akihiko, Sabe, Hisataka, Sato, Tosiya, Date, Hiroshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2019
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497483/
https://ncbi.nlm.nih.gov/pubmed/31114376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S200819
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