Hypoxia‐inducible factor 1 promotes chemoresistance of lung cancer by inducing carbonic anhydrase IX expression

Lung cancer treatment is difficult owing to chemoresistance. Hypoxia‐inducible factor 1 (HIF‐1) and HIF‐1‐induced glycolysis are correlated with chemoresistance; however, this is not evident in lung cancer. We investigated the effect of HIF‐1α and carbonic anhydrase IX (CAIX), a transmembrane protei...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Sowa, Terumasa, Menju, Toshi, Chen‐Yoshikawa, Toyofumi F., Takahashi, Koji, Nishikawa, Shigeto, Nakanishi, Takao, Shikuma, Kei, Motoyama, Hideki, Hijiya, Kyoko, Aoyama, Akihiro, Sato, Toshihiko, Sonobe, Makoto, Harada, Hiroshi, Date, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5269694/
https://ncbi.nlm.nih.gov/pubmed/28028936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.991
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