Statins may have double-edged effects in patients with lung adenocarcinoma after lung resection

Purpose: The epithelial to mesenchymal transition (EMT) is pivotal for driving metastasis and recurrence in lung cancer. Some in vitro reports have shown that statins suppress EMT by inactivating mutant p53 functions. Several clinical trials of conventional treatments with statins have been performe...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Nishikawa, Shigeto, Menju, Toshi, Takahashi, Koji, Miyata, Ryo, Chen-Yoshikawa, Toyofumi Fengshi, Sonobe, Makoto, Yoshizawa, Akihiko, Sabe, Hisataka, Sato, Tosiya, Date, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497483/
https://ncbi.nlm.nih.gov/pubmed/31114376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S200819
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